ADHD and anxiety both are slightly different mental health disorders with their unique signs and symptoms. Although most things of these two are different still there are some links between them. Today’s article will cover some of the basics of these two emotional disorders and talk about the relationship between ADHD and anxiety. At the same time, we also let you know about the best treatments for ADHD and anxiety.
Keep reading if you are also suffering from any kind of anxiety or ADHD symptoms. Let’s begin the journey of knowledge;
The most common link between ADHD and Anxiety
As mentioned, they are different in signs and symptoms, but in some severe conditions, their disorders may occur due to ADHD. For example, if you have been diagnosed with ADHD, you may also have another psychological disorder that the symptoms of ADHD can mask. According to medical research, about 60 percent {Outbound link, remove it if necessary}of people with ADHD have a coexisting or comorbid health condition.
Anxiety is one of those health conditions that often occur in individuals with ADHD. And, it is estimated that about 30 to 50 percent of children with ADHD also have anxiety. Please check more headings to learn more about the connection between these two emotional health disorders.
Basics of ADHD and Anxiety ADHD
ADHD is short-term used to indicate a mental health disorder known as attention deficit hyperactivity disorder. This condition is one of the most common neurodevelopmental disorders in children. It is usually diagnosed in childhood and often lasts into adulthood. Individuals with attention deficit hyperactivity disorder may have trouble paying attention and controlling behaviors.
Signs and Symptoms
Daydream a lot
Squirm or fidget
Talk too much
Forget or lose things a lot
Make frequent mistakes or take unnecessary risks
Have a hard time resisting temptation
Have complications getting along with others
Have trouble taking turns
Treatment:
Mild symptoms of ADHD can be managed by some behavioral and lifestyle changes. While in severe conditions, you can buy Adderall online to get the best treatment for ADHD.
Anxiety
Anxiety is a widespread mental health disorder that affects over a million people in the United States. This condition occurs as a response to our body against extreme stress. Anxiety is a feeling of fear or phobia about what is to come. For example, when you visit a new place, start a new job, attend an important interview or give a speech, you may feel a kind of fear called anxiety.
Sometimes, anxiety lasts for a short period and can motivate you to do better in your role. But, if your fear feelings are extreme, interfering in your daily life activities, and last longer than 6 months, you can have an anxiety disorder.
Signs and Symptoms
Increased heart rate
Rapid breathing
Restlessness
Trouble concentrating
Difficulty falling asleep
Sudden fear
Treatment:
Mild anxiety does not require any special treatment other than some changes in lifestyle and daily life activities. In severe conditions, you can buy Xanax online as the best anti-anxiety drug.
Difference between an Anxiety disorder and ADHD
Though a medical evaluation is necessary, parents or siblings may be able to tell the difference between anxiety and ADHD. The key is to observe how your symptoms change over time.
If you have ADHD, you will find it difficult to pay attention most of the time in any type of situation. On the other hand, if you have anxiety, you may be unable to pay attention to only problems that cause you to feel anxiety.
In people who have both of these disorders simultaneously, the symptoms may seem more extreme. For example, anxiety can make it more challenging to concentrate for people with ADHD.
Understanding co-morbidity
It is not clearly known why there’s a connection between attention deficit hyperactivity disorder and anxiety, and professionals do not fully understand what causes either condition. Genetics may be a reason behind both conditions and may also cause co-morbidity. Experts have also observed a number of other disorders that are commonly seen alongside ADHD, including:
Depression
Autism
Anxiety
Dyslexia
Sleep disorders
Substance abuse
Bipolar disorder
Possible causes for attention deficit hyperactivity disorder include genetics, premature birth, or environmental toxins. It’s possible that these causes could also contribute to anxiety.
Bottom line
Both emotional disorders are hazardous and can lead to some unpleasant accidents or physical and psychological problems in the patient. If they combined, the condition might be worse. Please take immediate medical help if you have any of these two or a combination of these two.
Xanax is the brand version of alprazolam belonging to the benzodiazepine class of drugs. Xanax acts as a central nervous system depressant. Benzodiazepines, also called tranquilizers, provide relief from anxiety and muscle spasms, produce sedation, prevent seizures, and induce sleep.
Basic Information About Xanax –
Xanax, as we know, is a brand-name drug sold in the United States. It is preferably prescribed to patients with anxiety and panic disorder. This drug went on sale in the year 1981, and since then, most the doctors prescribe it for the given purpose. There are a lot of types of Xanax that are sold in the US market. Though they are used for the same purpose, yet they are different in strength and color. The doctors recommend their patients with the right amount of drug dose according to their health and condition.
The category to which Xanax belongs is Benzodiazepine, also termed as “benzos.” The drugs from this category affect the mind and give a calming and soothing effect by acting as a depressant. Xanax is also put under the Controlled Substance Act as a schedule IV drug. Furthermore, this means that the drug has the potential of getting abused by the masses.
Xanax is available as both liquid and pill formulations. Xanax pills come in rectangular bars, shapes, round, oval, elliptical, and triangular shapes.
What Are The Slang Terms Used For Xanax?
Common street names or slang terms used for Xanax are:
Xannies
Z bars
Zanbars
Bars
Handlebars
Xanbars
Planks
Benzos
Bricks
Hulk Xanax
Green Monster
School bus
How is it Used?
Xanax is a prescription medication for the treatment of generalized anxiety disorder, transient symptoms of anxiety, anxiety related to depression, and panic disorder. Misuse of Xanax includes swallowing or injecting the drug.
Colored Xanax Bars (2mg)
There are 4 types of Xanax bars, that are most popular in the market due to their name, shape, and color (2mg bars). All are given below –
Green Xanax bars are Alprazolam, which is a powerful medication used for treating anxiety and panic disorders. Similar to any other Alprazolam, the Green Xanax bar affects the central nervous system of the patient, which produces a calming effect helping the patients by treating anxiety.
Several pharmaceutical companies are manufacturing Green Xanax bars, thus is available in an enormous variety of colors, shapes, and sizes. The reason for this is to provide each pill with a unique identity. Green Xanax bars are also imprinted with S 90 3 pills which are provided by manufacturers to give them recognition in the market. Thus it is also known as Green Xanax bars S 90 3.
Green Xanax typically contains active Alprazolam 2mg, which is similar to the White and Yellow Xanax bars in strength. They are thus making the Green Xanax have similar effects as the Yellow and White Xanax.
Green Xanax is available in triangular, rectangular, round, and oval shapes, which are available in Green Xanax bars 2mg and Green Xanax bars 3mg doses. Actavis, Pfizer, Mylan, and DAVA are some major pharmaceutical companies that manufacture this medication.
A White Xanax bar is a rectangular shape tablet that contains 2mg of the drug. Most drugs that we take are white. It is so because white is the standard color for medicines, and almost every pharmaceutical company produces medications of the same color.
This drug is considered to be a high dose for Xanax, and the dosage shall not be increased without consulting with the doctor. The tablet of a white Xanax bar is divided into four parts and can be taken in pieces as per the doctor’s advice.
It’s essential for patients to understand that 4mg is the maximum dosage for Xanax. In no condition, a person is allowed to take a higher dose without consulting from a health expert. On the streets, a white Xanax bar is also named as “sticks.”
As we just informed you that White Xanax Bar is a higher dose of Xanax and shall not be taken for another purpose.
Hence, you are advised not to quit the drug suddenly. Talk to a health expert and then follow the steps as per the recommendation.
Patients who have been taking Xanax for a while must know that the drug comes in many doses, colors, and shapes. Yellow Xanax is one of the most commonly used forms of Xanax that is prescribed to the patient as per their condition.
The yellow Xanax bar is quite similar in effect to that of the white Xanax bar. On a yellow Xanax bar, R039 is imprinted, which makes it unique from the other drugs. Also, as the name says Yellow Xanax bar is yellow and comes in the shape of a rectangle.
The most common name for Yellow Xanax on the streets is the “school bus.” This name is given after the color and shape of the drug. As said above, yellow Xanax and white Xanax are similar in effect; the strength of a yellow Xanax tablet is 2mg as well. It is essential to take the dosage pattern of yellow Xanax after consulting with a health expert.
You may have learned by now that all the tablets of Xanax that come in rectangular/bar shape are the most common dosage of the drug. Alprazolam or Xanax that comes in the form of a blue Xanax bar is similar to other Xanax bars. A yellow Xanax bar, green Xanax bar, and white Xanax bar are useful in the somewhat same manner.
A pill of a blue Xanax bar is also of the same amount as the rest of the other bar tablets of Xanax. The tablet is imprinted with B707 on one side and is rectangular. The strength of a blue Xanax bar is 2mg, which is quite like the other Xanax bars.
Side Effects of Xanax Bars –
The common side effects that could be seen in patients using real Xanax bars are:
Constipation
Nausea
Diarrhea
Blurred vision
Vomiting
Dizziness
Irritability
Upset stomach
Drowsiness
Trouble concentrating
Dry mouth
Muscle weakness
Slurred speech
Loss of interest in sex
Increased sweating
Insomnia
Lack of coordination or balance
Serious side effects that should be informed to the doctor immediately are:
Nervousness or fear
Difficult or labored breathing
Ear congestion
Hallucinations
Mood swings
Memory problem
Blurred vision
Suicidal thoughts
Body aches or pain
Severe abdominal or stomach pain
Seizures
What Are The Risks Associated With Xanax Use?
Xanax is a tranquilizer that slows down normal brain function, which results in adverse effects such as shallow breathing, slurred speech, fatigue, sluggishness, lack of coordination and disorientation, and dilated pupils.
Higher doses of Xanax cause memory impairment, loss of coordination, paranoia, irritability, and suicidal thoughts. Some people also become agitated or aggressive after taking Xanax. Using Xanax with any other central nervous system depressants, particularly alcohol, can slow breathing or heart rate, or both. It leads to severe consequences, even death.
Continued use of Xanax leads to dependence even at recommended doses. Withdrawal symptoms may also appear if a person stops using Xanax abruptly. As all tranquilizers slow brain activity, when someone stops taking them, rebound effects can occur, such as seizures.
Tolerance to Xanax can also occur. People require larger than previous doses to achieve similar effects when they develop tolerance. It often leads to overdose as the user takes more than prescribed doses to get the results.
Prescription tranquilizers like Xanax can be highly addictive, as a person needs to continue the doses of a drug despite its harmful consequences.
What Are Some Signs of Xanax Use?
Signs of Xanax use at a glance:
Suicidal thoughts
Paranoia
Irritability
Memory impairment
Dilated pupils
Loss of coordination
Disorientation
Fatigue
Sluggishness
Shallow breathing
Slurred speech
Fake Xanax Online
Buying fake Xanax is one of the most menacious risks of purchasing Xanax through online pharmacies. Fake Xanax pills could contain several hazardous ingredients, some of which are even not for human consumption.
Moreover, fake Xanax looks precisely like the real Xanax pills and even comes in the proper packaging. It gives you no clues that medicine is fake. Some companies also sell drug testing kits online that are unreliable and fake too.
Misusing the prescribed drug is dangerous for you, but using fake medicine is even more critical.
Buying Xanax Online: Is it safe?
Buying any drug, say it’s a prescription drug, designer drug, or illegal drug, online is never safe. There are too many risks associated with it. Purchasing drugs such as Xanax online does not only possess a chance to your physical health but your financial health also. You can end up in criminal charges or severe overdose, causing coma and death.
Buying Xanax online seems to be the best option if you are addicted and experiencing extremely discomforting withdrawal symptoms. You don’t need to be addicted to Xanax for a lifetime. There are many ways out of your addiction. There are numerous benzodiazepine detox programs. You can take help from one of those programs, or you can consult a health care expert about your Xanax addiction.
Buying Xanax online can be unsafe and precarious. Only buy Xanax online from trusted legal pharmacies that sell genuine medications approved by the FDA.
How Long Does Xanax Last?
Even though the half-life of Xanax is around 11 hours, still it is not considered a long-lasting medication as the effect of this medication lasts for about four hours only. This means that the Xanax present in the patient’s system after 4 hours is ineffective, which is the reason why it is used several times a day.
The dosage of Xanax depends upon the doctor’s prescription and the severity of the symptoms. It is the main reason why doctors do not recommend using Xanax for the treatment of chronic anxiety.
Facts About Xanax That Can Be Alarming –
Although Xanax has a low potential of abuse as compared to the other drugs, it is high among the most abused drugs in the United States. Here is a list of facts that will tell you about the warnings that are related to Xanax usage.
There is an increase of 67% of the people in the United States since the year 1996 who have filled in for Xanax prescription.
The abuse of Xanax can be deadly as in the year 2015, approx. Nine thousand people died due to benzodiazepine drugs.
There were four times more deaths between the years 1996 and 2013 due to the overdose of Xanax and Valium.
There was an estimate of about 10 to 25 percent of Xanax users who were dependent upon the drug due to long-time use.
There is an increment of 17% in Benzodiazepine prescription since the year 2006. It merely means that overall, 94 million more prescriptions are assigned to people every year.
The combination of Benzos, along with an opioid drug, can cause lethal health issues. There have been 8,000 to 9,000 deaths in the year 2015 due to the combination of benzos with opioids.
Abuse Of Xanax Among Teenagers –
The FDA and other drug authorities are more concerned about the dependency of Xanax on teenagers. There can be a high threat to the health of teens with the abuse of Xanax. They may become physically and mentally dependent upon the use of Xanax. This not only occurs when a person misuses the drug, but it can also happen when you are taking the medicine as per the prescription. Therefore, it can be deadly at times.
According to the reports of the National Survey on Drug Use and Health, there is a huge count of younger people taking Xanax and other Benzodiazepine drugs for non-medical use. It has also been reported that more than 10 percent of the younger people between the age of 18 to 25 are abusing Xanax for its sedative effect. In fact, this rate is just double of people who are above the age of 26 and abusing the drug.
In What Ways Will Xanax Abuse May Impact The Lives Of Teens’
Apart from making them physically and mentally dependent upon the drug, Xanax can also affect the lives of Teen in the following ways –
It can have a negative impact on your performance level in school or work.
You may not be in touch with your close friends.
Your family relations will be disrupted.
You might be at a much higher risk of injury due to accidents.
You will be high on abusing drugs and more than one substance at a time.
Insomnia is a sleep disorder found annually in more than 40 million people in the USA. Individuals suffering from insomnia often find it difficult to fall or stay asleep, wake up frequently during the night and have a problem going back to sleep, wake up too early in the morning, and feel tired upon waking.
Primary Insomnia: Primary insomnia is the one in which a person has sleep problems that are primarily due to insomnia and not directly associated with any other medical conditions.
Secondary Insomnia: Secondary insomnia is the one in which a person has a sleep disorder due to some other medical conditions such as pain, depression, asthma, arthritis, cancer, or any other health issue, or medications or drugs they are taking.
https://www.youtube.com/watch?v=gvfCpwjWjiA
Causes of Insomnia –
There can be three types of reasons that can give rise to insomnia:
Medical Causes:
Nasal and sinus allergies
Gastrointestinal problems
Endocrine problems
Arthritis or asthma
Neurological conditions
Chronic pain
Sleep apnea
Prescription drugs
Psychological Causes:
Stress
Anxiety
Depression
Lifestyle Changes:
Sedentary lifestyle
Lack of exercise
Time zone or shift changes
Substance abuse
Poor sleeping or eating habits
Treatment of Insomnia –
Lifestyle Changes And Exercise
Employ a proper sleep routine. Change sleep habits and exercise properly for 30 minutes a day. Take a balanced diet and do not overeat before sleeping. Moderate aerobics, brisk walk, swimming, and yoga can help sleep better. Avoid drinking too much caffeine or overheating the bedroom before going to sleep.
Medical Treatment
Doctors may prescribe certain medications for the treatment of insomnia based upon the medical status and other health conditions of a patient. Ambien is a prescription medication helpful in treating insomnia.
Ambien is a prescription medication to treat insomnia.
It is the brand name version for generic zolpidem drug.
Ambien belongs to a class of sedative-hypnotics drugs, which acts on the brain to slow down its activities and thus help sleep peacefully.
Ambien is the most prescribed sleep medication in the USA.
It comes in both immediate-release and extended-release oral tablet formulations.
Ambien is a Schedule IV controlled substance under the Controlled Substance Act 1970.
Uses –
Ambien is a non-benzodiazepine sedative and hypnotic useful for the short term treatment of insomnia or sleep-related conditions. It is an agonist of type A GABA receptor of the imidazopyridine class. It works by boosting GABA (Gamma Amino Butyric Acid) effects in the central nervous system by binding to type A GABA receptors as benzodiazepines.
Ambien immediate-release tablet has an average half-life of two to three hours. The half-life increases in patients with liver problems.
Ambien makes a person fall asleep as soon as you go to bed and helps in restful night sleep. It decreases sleep latency for up to 35 days. Efficacy of Ambien is up to four to five weeks in controlled clinical studies.
Dosage –
Adult Dosage:
It is advisable to use the lowest effectual dosages of Ambien. Initiate the dose with 5 milligrams for women and 5 or 10 milligrams for men, given before going to bed. Take the dose at least seven to eight hours before you need to wake up. Give 10 milligrams dose only if the 5 milligrams dose is not adequate to provide desired results. A 10mg dose increases the risk of high blood levels in the morning and leads to next-day impairment of alertness. Do not exceed a dose of 10mg once every night in any case.
The recommended dose for women is lesser because they have a slower clearance of zolpidem.
Special Population:
Debilitating or elderly patients and patients with mild hepatic impairment are especially sensitive to the side effects of Ambien. Doctors recommend a dose of 5mg for these patients given once at bedtime.
Avoid Ambien for patients with severe hepatic impairment as it can cause encephalopathy.
Do not take Ambien with a meal as it slows the effects of the medication.
Side Effects –
Common side effects of Ambien include:
Drowsiness
Headache
Dizziness
Lightheadedness
Tiredness
Feeling drugged
Unsteady walking
Nausea
Vomiting
Constipation
Diarrhea
Severe adverse effects of Ambien include:
Complex sleep behaviors
Abnormal thinking and behavior changes
Central Nervous System Depressant Effects
Next day impairment of alertness
Severe Anaphylactic and Anaphylactoid Reactions
Withdrawal symptoms
Precautions –
Follow some special precautions before taking Ambien:
Inform your doctor if you have hypersensitivity to any active or inactive ingredients of the medication. Check the list of ingredients before taking Ambien.
Tell your doctor about all the concurrent medications, prescription or non-prescription, nutritional supplements, vitamins, and herbal products you are taking.
Never take more than one pill in a single night. Do not take Ambien and any other sleeping medication concurrently.
If you are taking any herbal products for a sleep disorder or any other medical condition, inform your doctor about that before taking Ambien.
Consult your doctor about your history of substance or alcohol abuse or addiction. Also, consult the doctor if you have or ever had depression, mental illness, suicidal thoughts, sleep apnea, breathing problems, and liver or kidney diseases.
If you are in the last trimester of your pregnancy or a breastfeeding mother, consult your doctor about it.
Elderly patients are generally more vulnerable to the side effects of sleep medications. Doctors may recommend other treatment plans for older adults.
Do not forget to tell your dentist that you are taking Ambien before having dental surgery.
Ambien causes drowsiness, decreased mental alertness, and lightheadedness. Be extra careful while going out of bed, standing up from a lying or sitting position, driving, operating machinery, or doing any work that needs alertness.
Mixing Ambien with alcohol or any other CNS depressant can elevate the risk of side effects.
Ambien also causes sleep-walking and other activities while sleeping like making phone calls, cooking, eating, and having sex. Immediately consult a doctor if you are doing any of these sleeping activities.
Where To Buy?
People can buy Ambien online through online pharmacies. You can also buy the medication on drug stores and pharmaceutical shops. However, order Ambien online to get handsome discounts and genuine medication through our pharmacy.
Novel Coronavirus, which is behind the onslaught of COVID-19 disease, comes from the family of coronaviruses. These viruses can cause illnesses like the common cold, SARS (severe acute respiratory syndrome), and MERS (Middle East respiratory syndrome). In late 2019, in the Wuhan province of China, a new coronavirus was identified as a cause of a disease outbreak in the region.
The virus itself is called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease it causes in people is known as coronavirus disease 2019 or COVID-19. In March o 2020, the World Health Organization (WHO) declared the COVID-19 outbreak as a pandemic, and ever since major public health groups like WHO U.S. Centers for Disease Control and Prevention (CDC), etc. are monitoring the epidemic and updating their websites with the latest information about the outbreak.
These public health groups are also issuing guidelines regarding the prevention and treatment of this illness.
Symptoms
COVID-19 symptoms start to appear within 2 to 14 days after the exposure. The time between a person getting exposed to the virus and showing signs is called the incubation period. It is the most crucial time for a person, as, during this period, a person is most likely to spread the disease to others.
Common COVID-19 symptoms can include:
Cough
Fever
Tiredness
These are the main symptoms of this disease, but other symptoms can also indicate that the coronavirus has infected a person.
Other symptoms of coronavirus disease include:
Muscle aches
Headache
Sore throat
Chest pain
Shortness of breath
Difficulty breathing
Chills
Loss of taste or smell
These symptoms are not all the signs that a person can exhibit after getting infected with the virus. Organizations like WHO and CDC are monitoring the situation and adding new symptoms in the list
Some new symptoms of COVID-19 include:
Nausea
Vomiting
Diarrhea
Congestion and runny nose
The severity of the symptoms can vary between individuals, and children generally have milder symptoms than adults. Not everyone shows all signs of this disease. Some have very few symptoms, while others might not exhibit any of the signs of the illness.
People with already existing chronic medical conditions such as lung disease, severe obesity, heart disease, diabetes, chronic liver disease or kidney disease, or compromised immune systems might be at higher risk of serious illness.
When to visit the doctor?
If you have any of the COVID-19 symptoms or have come in contact with someone diagnosed with this disease, you should contact a medical professional immediately. Tell them about your symptoms or exposure before you show up there for your appointment.
If the severity of the symptoms is high, you should not waste any time and immediately get medical attention. The symptoms that might warrant an emergency response can include:
Persistent chest pain or pressure
Trouble breathing
New confusion
Blue lips or face
Inability to stay awake
It would be best to let the medical professional know about any chronic medical condition that you might have, such as lung disease or heart disease.
What Causes COVID-19?
Exposure to the new coronavirus (SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2) results in COVID-19 (coronavirus disease 2019).
Right now, human-to-human transfer appears to be the primary cause of spreading this disease. Data shows that the virus spreads from person to person when they come in close contact (usually within 2 meters or six feet).
It also spreads sneezes, coughs, or talks through the droplets that the other person can inhale. The virus can also spread if a person touches a surface that contains the virus and then touches their nose, eyes, or mouth.
Prevention
There is no cure available for COVID-19, but there are various steps that a person can take to reduce the risk of infection. CDC and WHO recommends the following precautions for COVID-19:
Stay at home as much as possible.
Keep a distance of about 2 meters (6 feet) between yourself and others.
Wash your hands frequently with water and soap for 20 seconds or use a hand sanitizer that contains at least 60% alcohol.
Avoid touching your mouth, eyes, and nose.
Disinfect and clean the frequently touched surfaces, like light switches, counters, electronics, and doorknobs.
Avoid events and mass gatherings.
Use a cloth mask to cover your face in public places. Using a surgical mask is not required as an ordinary cloth mask is enough to get the job done.
Use a tissue or cover the nose and mouth with your elbow while sneezing or coughing.
Throw the used tissue and wash your hands immediately.
Do not share items such as towels, beddings, glasses, dishes, and other household items.
Do not go to the office, school, or any other public area if you feel sick.
Avoid using public transport, taxis, and ride-sharing services if you are going to visit a doctor.
Because of the unavailability of any vaccine for COVID-19, it is crucial to take all the necessary precautions. People with chronic health issues should also consult with their doctor for any additional precautions they need to take. They have a very high risk of contracting the illness and suffering severely from it.
People all around the world are facing a different kind of health issues. These could be about your physical health or psychological health. It is important to come face to face to the fact that mental health issues exist in our society, and people should know about them and their symptoms. There are several psychological issues that are seen occurring in people. Most of them are due to the lifestyle changes that we have adapted towards.
What Do You Understand By The Word – Anxiety?
In standard terms, a person will feel anxiety as an outcome of stress. Many people feel this stress because of some fear or apprehension that they think is around the corner. A person may feel a kind of tension in situations like – going for a job interview, having a financial crisis, and many such fearful things that happen in our everyday life. The person may become nervous, and there starts the act of anxiety.
There can also be a time when a person may feel this stress regularly for more than six months or so. You should know that in such a case, you need to take medical advice from a health professional. No matter what, you must not try to purchase a drug for anxiety treatment by yourself. Always seek help from a medical professional to get a proper recommendation for managing the symptoms of anxiety.
In general, anxiety is a type of disorder that is the most common phenomenon of emotional disorders affecting a person. These types of disorders may occur at any point in time and any age. There have been studies that say women are more likely to develop the symptoms of anxiety as compared to men.
The Types Of Anxiety Disorder –
Many kinds of anxiety disorders may occur in different people. Some of the diseases that usually happen are given below –
Phobia – This type of condition occurs when a person is in excessive fear of a situation, an object, or an activity happening around him/her.
Social anxiety disorder – It is an extreme fear of meeting people in public and getting offended by others misjudging them.
Panic disorder – This is meant to be experiencing panic attacks at a recurring point of time without having a proper timing or schedule. A person who suffers from panic disorder is always in fear when a panic attack may occur.
Obsessive-compulsive disorder – It is a condition where a person may run through the same thoughts in his/her mind that are irrational. As a result of this, the same tasks and behavior are repeated on a daily basis.
Post-traumatic stress disorder (PTSD) – This a condition that will only occur when a person has faced a traumatic event in the past.
Illness anxiety disorder – A person who is conscious of his/ her most of the time tend to be suffering from this disorder.
What Are The Common Symptoms That Occur When A Person Suffers From Anxiety?
There will difference in the level of experience when a person suffers from anxiety. Not every individual will have the same feeling of anxiety as the other person. You should understand that the feels may range from – feeling irritated or to the extent of rapid heartbeats.
The person may also feel a disconnect between the heart and the brain due to its uncontrolled behavior. There are some other ways through which a person will experience anxiety, like – nightmares, painful thoughts, panic attacks, or memories that are harsh on your mind. You may feel worried, and fearful thoughts will run inside your mind. Along with this, the person will fear a particular event that has happened in the past or a place due to some uncomfortable connection.
Below are listed some of the general symptoms of anxiety –
Rapid heart rate
Trouble in concentration
Breathing heavily
Feeling restless
Unable to fall asleep
It’s not necessary that every person will face the same symptoms of anxiety. For some, these could be way too different from the one listed above. Hence, you need to know that there can be other symptoms of anxiety that may occur depending upon the person’s condition.
How To Tell If A Person Suffers From Anxiety?
Firstly, you need to know that a single test cannot define if you have the symptoms of anxiety or not. There is a lengthy process required for the diagnosis of anxiety. It will include – physical examination, questions related to psychology, and mental health evaluation.
Sometimes, a doctor may also tell you to undergo tests of a physical examination that includes a blood test and urine test. It is usually done so that the doctor could reach out to the actual cause of anxiety disorder. It is rare, but sometimes there are some underlying medical conditions that are responsible for causing anxiety. There can be several other tests that will determine the level of stress you are currently experiencing.
What is An Anxiety Attack?
When a person goes through an anxiety attack, there can be different feelings that run at the same time. It can be a feeling of overwhelming apprehension, distress, fear, or worry of a situation. Most of the time, an attack of anxiety is build up slowly in your system. It may get worse when a stressful situation happens to occur in the near future.
The anxiety attacks may vary from person to person and also their symptoms. It is so because most of the symptoms of anxiety attacks do not happen to every person dealing with anxiety issues. They may change over a period of time.
The symptoms of an anxiety attack that are common are –
Feeling dizzy
Falling short of breath
Sweating
Chills in the body
Restlessness
Worry
Mouth gets dry
Fear
Numbness
Tingling sensation in the body
Many of people may not know that the symptoms of an anxiety attack are quite similar to that of panic attacks. To be sure if you suffer from anxiety or not, take help from your doctor.
What Are The Treatments For Anxiety Disorder?
Although anxiety is considered to be a severe problem, there are some treatments through which you can overcome this disorder. The treatment of anxiety is basically divided into two parts – medication and psychotherapy. Though they both (medication and psychotherapy) go hand in hand, in a mild case, doctors may only prescribe you for therapy and no drugs or vice versa.
A person will get treated with the help of medicines that acts as antidepressants and sedatives. The work of medicine is to balance the formation of chemicals and prevent a person from episodes of anxiety. Medication will help in managing the most severe symptoms of anxiety disorder.
While on the other hand, therapy programs will be run by a therapist or psychologists. They will help you in learning strategies and different tools through which you will be able to cope with the symptoms of anxiety.
Is There A Correlation Between Anxiety And Depression?
There is a terminology that says – if a person is suffering from an anxiety disorder, he must be dealing with depression as well. Although anxiety and depression may occur at two different times, it is also observed that both of these disorders may occur at the same point in time.
In other terms, anxiety is sometimes also referred to be a symptom of severe depression in a person. Likewise, when the condition of a person starts getting worse due to depression, it will trigger the problem of anxiety. Both these disorders (anxiety and depression) can be managed with the help of medication and psychotherapy.
The street price of Xanax (Alprazolam) varies from place to place and country to country. In the United States, Xanax prices can vary a minimum of $2 for a 1mg pill to a maximum of $10 for the same strength pill.
However, on the internet through the darknet, prices for this medication can be much less. You may buy enough quantity of Alprazolam (the non-branded drug name) about 500 Xanax pills in a minimum amount of money (about $50).
Xanax On The Streets
This drug is one of the most popular and highly addictive prescriptions pharmaceutical available today. This high demanded drug is not only available in pharmacies, however, but on the streets of the U.S, Europe, and around the world. The street value of this medication has been stable over the last twenty years, but the prophecies indicate that the street price of Xanax will decrease in the future.
The street price of this product mainly depends on the supply and demand in specific locations. There are many Xanax dealers in some states of the United States, while in some European countries, there are many addicts and only a small number of dealers.
An estimated average value of Xanax on streets is about $2 per 1 mg, $4 per 2mg, and $6 per one Xanax bar.
Xanax Price On The Streets Of The United States
On the east seaside, dealers typically sell Xanax for $2 per 1mg or $4 per 2mg. In this region, drug addicts are willing to pay up to $20 for a 2mg pill. In the state of Pennsylvania, Philadelphia is the largest and most populous city in the United States.
Addicts in this thriving metropolis can easily attain Xanax for $5 per 2 mg pill.
The situation of Xanax prices in New England is slightly different. In this area, Xanax street prices may be up to $10 for 1mg of Alprazolam.
Texas, the second-largest U.S. state in southern regions, this drug was used to be very expensive before 2010. Users could purchase 2 mg Xanax pills for $5. In response to severe economic conditions, the price of this anti-anxiety drug has gone up, and today users may pay up to $5 to $6 for one 2 mg bar. In South Carolina, this narcotic typically costs $7 per 2 mg.
In midwestern states such as Michigan, users can purchase a 0.5mg Xanax pill at $3. While on the west coast, such as in California, prices vary from $3 to $7.
Xanax Prices On The Darknet
Darknet is an anonymous part of the internet where illegal activities are often carried out. You may order a Xanax bar at $2 to $3 through the Darknet. On the Darknet, dealers, and addicts also may buy pure Alprazolam powder and make the pills themselves. An amount of Alprazolam equivalent to 500 Xanax pills can be purchased online for only 450.
The main significant difference between Xanax street and online prices is that prices on the Darknet are not as stable as prices on the streets.
It is the brand name of Alprazolam which is a prescription medication. It is a triazole analog of 1,4 benzodiazepine (short-acting benzodiazepine) a class of central nervous system active compounds.
The chemical name of this drug (Alprazolam) is 8-chloro-1-methyl-6-phenyl-4h-s-triazolo{4,3-a} Benzodiazepine.
Xanax is a white crystalline powder that is soluble in methanol or ethanol but not in the water at physiological pH.
Every tablet of Xanax, for oral administration, contains 0.25 mg, 0.5 mg, 1, and 2 mg of Alprazolam. XANAX tablets 2 mg are available in a combination from which can be divided into 4 dosages.
Some Inactive Ingredients:
These tablets contain some inactive ingredients like Cellulose, corn starch, docusate sodium, lactose, magnesium stearate, silicon dioxide, and sodium benzoate.
Indication
Anxiety Disorder
Panic Disorder
XANAX tablets are used to the management of anxiety disorder. Xanax is a short-term option to help manage symptoms of Anxiety. Anxiety associated with the stress of daily life does not need treatment with an anxiolytic.
Xanax is especially recommended for the treatment of Panic disorder with or without agoraphobia. Benzodiazepines impact receptors for gamma-aminobutyric acid (GABA) and provide a calming effect on persons with anxiety.
Dosage
Professionals should administrate your dosage as per your physical and mental condition. It is essential to take the lowest usual dosage for a short duration.
Dosage for Anxiety Disorder
Dosage of Panic Disorder
Initial dosage: 0.25 mg to 0.5 mg three times a day as needed
Dosage adjustment: You may increase your daily dosage as per the recommendation of your doctor at intervals of 3 to 4 days
Maximum dosage: 4 mg per day
Initial dosage: Greater than 4 mg per day as needed
Dosage adjustment: You may increase your daily dosage as per the recommendation of your doctor at intervals of 3 to 4 days
Maximum dosage: 10 mg per day
Dose Titration
The initiated dosage of Xanax is 0.5 mg three times a day. The initial dosage can be increased at the intervals of 3 to 4 days in increasements of no more than 1 mg per day.
2mg – Color: White, Green, and Yellow, Shape: Oblong, Imprinted: “XANAX” on one side and “2” on another side
Keep Xanax bars and pills at room temperature (20 to 25 degrees Celsius).
Types of Xanax
This medication is available in various kinds of colors. Many pharmaceutical companies are manufacturing Xanax in different types of colors and shapes with several strengths.
Here are the most prescribed types of XANAX, which are,
Green Xanax Bar
Green Xanax pills are sold by one specific pharmaceutical company. These pills come with 2 mg of active Alprazolam like white and yellow bars.
There is no difference in shape between white Xanax and Green Xanax. Based on their strength and color, these bars are also known as Hulk Xanax and Monster Xanax.
You should take these pills under strict medical supervision as it contains a very high dose of Alprazolam which may be habit-forming or cause an adverse effect.
Generally, these pills considered stronger than white pellets. The typical price of green Xanax bars is $ 6, which is changeable at the street stores as per demand and supply.
Pink Xanax
Pink Xanax is available in a 0.5 mg dose which is the second initial dose of Xanax. These bars are generally prescribed for anxiety and Panic disorder.
Pink Xanax is not produced widely for addiction purposes, and you may purchase it online with the prescription of your doctor. These pills are also known as football based on their shape.
This type of Alprazolam is legally available by physician-authorized prescription only, but many peoples used benzodiazepines for addiction purposes.
White Xanax Bar
These bars are available in two-milligram doses. White Xanax Bars come in a combination of four separate treatments which can be divided into 4 doses.
These bars are the high dose of Xanax the same as Yellow Xanax Bars and Green Xanax bars. White Xanax bars come in a rectangular shape which is also known as sticks in the streets. These bars produce strong sedation within minutes of being consumed.
This high dosage of Xanax is not advisable to quit cold turkey; it can produce dangerous withdrawal symptoms.
Yellow Xanax Bar
Yellow Xanax bars are the same as white and green Xanax bars. There is only the color and company difference between these three. These bars are the generic form of Xanax, which has the same effect as the name brand version of the drug.
It is an extremely high dosage of the drug-like White and Green Xanax bars. It is crucial to make a distance with these bars after finishing the medication cycle.
Blue Xanax
This Xanax pill offered in a one-milligram dose. These bars sold in an elliptical or oval shape. Blue Xanax pills are often scored like the Xanax bars are, so that users can break them into smaller pieces.
It is a middle dose of Xanax which you can be used after the second initial dose. Blue Xanax bar also offers 0.5 mg of Alprazolam which comes in a round or football shape.
Blue Xanax pills are available by prescription only having 031 imprints on them.
Orange or Peach Xanax
These pills come with the strength of 0.5 mg of Alprazolam which can be taken at the start of treatment. Orange Xanax bar also offers 0.25mg dose of Alprazolam which is the perfect initial dosage of Xanax.
This type of Xanax comes in small pills with an oval shape. Peach Xanax pills are good to use in persons with a less severe medical or mental disorder.
Liquid Xanax
Xanax is also available in liquid form for persons who cannot take the drug in pills or bars form. This type of Xanax is available in a small bottle. The effect of Liquid form is the same as other forms of Xanax.
This type of Xanax, generally prescribed for the treatment of anxiety disorder, panic disorder, and insomnia even for the treatment of withdrawal symptoms of alcohol.
Purple Xanax
These circular or elongated tablets contain 1 mg Alprazolam and are marked with the drug’s name and 1.0. The usually recommended dose is 0.25 or 0.5 mg in anxiety disorders.
A maximum of 4 purple Xanax footballs is the highest dose.
Forms of Xanax
Xanax is available in some common ways, which are,
Extended-release Form: This form of Alprazolam is dissolved slowly and provides a relaxing effect of 24 hours. This form of Xanax is only for use in persons with the Panic disorder.
Immediate-release form: It is the most common form of Alprazolam, also known as bars because of their shape.
Oral Form: This form of Xanax is useful in persons who can not take Xanax in pills or bar form.
Orally Disintegrating Tablets: These tablets are used as an option for persons with trouble swallowing.
What Precautions Can I Take While Using Xanax Bars?
Xanax is a prescription medication take it with some necessary precautions. Taking precautions ensures the 100 percent benefit of the drug and protects the user from the adverse effects of medication.
Some Necessary Precautions
Using Xanax on empty stomach may cause constipation symptoms like nausea and vomiting. Take it with a glass of water after eating food.
This medication can also induce extreme constipation and dry mouth. Take a sugar-free hard candy to avoid the dryness of the mouth and taking a drug as per your doctor’s recommendation may help with relief from constipation. In case of any other problem take the help of your health advisor.
If you have missed a dose take it as soon as you remember but do not take it at the time of another dosage. Taking two or more than two dosages of Xanax may cause interaction and side effects.
It is not good to take this medication during the pregnancy period. It may be dangerous to you and your unborn baby.
Do not take Xanax if you are a nursing mother, it may react to your breast milk and harm your baby.
Taking other drugs or alcohol may interact and cause some severe symptoms to like,
Drowsiness
Lightheadedness
Sleeping for an extended period
Cognitive impairment
Sluggishness
Vomiting or nausea, etc.
Why Do People Buy Xanax Online?
The prescription of Xanax is for a maximum of eight months. The use of Xanax after eight months is not recommendable; however, some people want to use Xanax for longer once they are dependent on the drug. Addicted people with an average addiction take 20 to 30 pills of Xanax in a day. At this rate, their medicine reserves deplete at a rapid pace. It is a reason why people often choose to buy Xanax online.
People buy Xanax online for a majority of reasons, including:
Addicted people buy Xanax online who need a fast and convenient way to buy the drug.
People who abuse cannot get a prescription from the doctor that is why they go for online purchasing
Some people who cannot afford Xanax need a cheaper solution which they find online
People who want to remain anonymous buy Xanax online through digital currencies.
Dangers of Buying Xanax Online
Buying Xanax online without a prescription is illegal. Apart from this, it is also dangerous for several other reasons:
Illegitimate Pharmacy: You could be purchasing the medication from an illicit pharmacy. However, many online pharmacies are legitimate, but most of them are illegal, with no regard for consumers’ safety or health. These pharmacies are not as trustworthy as their only aim is to make money.
Xanax Counterfeit: The Xanax you buy online could be counterfeit. If you are purchasing a much cheaper Xanax online without any prescriptions, there is a good chance that the drug is not real. Illegal online pharmacies are selling fake pills to unsuspecting customers. These counterfeit pills contain dangerous ingredients, such as incorrect active ingredients. They could also include life-threatening drugs such as fentanyl.
Risk of Financial Information: There is also a chance that your financial information is at risk. Illegal pharmacies steal credit card information from customers.
Risk of Fine or Imprisonment: Buying Xanax online without a prescription is illegal. You will have to pay the price if you are caught doing so. Purchasing Xanax online from another country, shipped illegally into the USA, can let you pay felony charges or up to 10 years imprisonment.
Matter of Health and Well Being: Your health and well being could suffer from buying fake or illegal drugs online. If the Xanax you ordered online is fake, tampered with, or combined with other medications, you could face severe, even fatal side effects.
Dilaudid is a part of a group of drugs that are chemically similar to opium and prescribed to be taken as pain killers. The brand name of the drug is Hydromorphone and by its name, you can easily guess that the drug is derived from morphine.
Although people buy Dilaudid online because it is prescribed to be taken as a painkiller and is considered to be stronger than morphine, it is less likely that a person will get addicted to the drug if taken by someone in a larger quantity.
What are the side effects of Dilaudid?
Most people who buy a prescription drug tend to take it more than prescribed, mostly by injecting the drug into their bloodstream, mainly to get high. In such a case, the drug may cause a strong euphoria. Some people who tend to abuse the drug take it by mixing it with other opiates like heroin.
However, the signs of drug use or abuse depend on the person who is indulging in the intake or the quantity of the drug he has taken so far. Therefore, the signs of drug use or abuse in the case of Dilaudid are:-
Dizziness
Nausea
Vomiting
Stomach ache
Constipation
Finding it difficult to breathe
Fainting
If you want to know more about these signs and help yourself from becoming a victim of these signs of taking the drug, the best way to do so is to buy Dilaudid online in the USA and from an online pharmacy that is able to provide you with a prescription.
Withdrawal Symptoms of Dilaudid:
As you must have understood by now that if you buy Dilaudid online and start taking the drug more than prescribed or beyond the prescribed limit, you are bound to face the hazardous consequences of doing so, including wanting to take the drug more and more.
The drug may or may not work for everybody but if you suddenly stop the intake of the drug after a long time on knowing that the drug is not proving to be effective for you, you are bound to face the withdrawal symptoms of the drug.
So, the best method to save yourself from becoming a victim of the drug’s withdrawal symptoms is by slowly decreasing the intake of the drug and then stopping its intake.
But for now, let us discuss some of the withdrawal symptoms of the drug:-
Tramadol is a drug that is used as a painkiller. It is a narcotic-like severe pain killer for adults. The working of Tramadol is to blind the receptors present in the brain which are responsible for transferring the sensation of pain from the whole body to the brain.
Tramadol comes in three forms Instant release tablets, Extended-release tablets, and capsules. Instant release tablets release in our body immediately while extended-release tablets start its action slowly over time. Tramadol is a potent drug, so it should be taken under the supervision of the doctor or pharmacist. Tramadol can be administered with a combination of other medicines.
Working of Tramadol:
Tramadol is a drug that belongs to the “opioid agonists” family of drugs. All members of this family show similar working properties. Tramadol blinds the receptors in the brain that’s why receptors carry less pain message throughout the body to the brain, and our brain feels pain in decreased form.
Side Effects of Tramadol:
The most common side-effect of this drug is you may feel dizziness, headache, nausea, vomiting, drowsiness, constipation, sweating, lack of energy, dry mouth, etc. These are the most common symptoms of Tramadol. Some people may feel some different effects also, if you are feeling as above or something else after taking Tramadol and if the problem continued, then, you must consult your medical practitioner.
Some severe side-effects of Tramadol are fast heart rate, high blood pressure, higher body temperature. You may feel unable to control the movement of your body(lack of coordination). You may feel nausea, vomiting, agitation, hallucination.
The other serious side effects of this drug are serious breathing problems like slowed breathing rate, very shallow breathing, fainting, dizziness, or confusion.
Drugs Which Can’t be Used With Tramadol:
Carbamazepine is one of the examples of medicines that can not be used with Tramadol, because if you use this medicine with Tramadol, then the working property of Tramadol is effected. Tramadol may become less effective in relieving your pain on taking with this drug, or some severe side-effects may also occur. The combination of these two drugs decreases the total amount of Tramadol.
Tramadol Precautions:
We have provided for you a list of precautions that you must take to avoid the harmful effects of the drug. Follow the guidelines that are given below –
The tablets of Tramadol should not be used by any child who is younger than 12 years. As we know, Tramadol is a habit-forming drug, and giving it at a younger age will develop a dependency.
Take the tablets of Tramadol as prescribed by your health expert. You can also follow the steps given on the prescription label of the drug.
A woman who breastfeeds her child should not take this medicine. The drug content may get transfer to the body of the baby and hence, may cause severe harm.
The extended-release tablets of Tramadol should not be given to people under the age of 18.
Do not overdose or misuse the tablets of Tramadol. It will get you addicted to the use of medicine, and severe health issues may arise.
Someone who is Allergic to opioids must not take this medicine. Taking Tramadol may even worsen the allergies like hives or rashes over the skin.
If someone drinks alcohol or is a habitual consumer of alcohol, then you should not take Tramadol. A combination of alcohol, along with Tramadol, will increase the effect of the drug and may also cause severe drowsiness.
Is Tramadol Addictive?
Tramadol is an opioid-like medication. It treats severe pain by acting on the brain and changing the way the body feels and responds to pain. Tramadol works similarly like a narcotic, and hence, it is also an addictive medication. It acts on the brain resulting in causing an addiction to the drug.
The misuse, overdose, or more prolonged doses of the tramadol can cause severe addiction. Even at regular doses, it can be habit-forming. To prevent the addiction caused by tramadol, take it exactly as prescribed by the doctor. Stop the medication gradually when it is no longer needed.
Do not use tramadol if you are prone to substance abuse or addiction.
Can It Cause Withdrawal?
Tramadol can cause dependence. Do not stop taking the medication at once, as it causes severe withdrawal symptoms. Gradually lessen the dosage of tramadol, as directed by the doctor.
Withdrawal symptoms differ in different patients. Many factors are responsible for causing withdrawal. The withdrawal caused by tramadol is influenced by:
Patient’s age
Patient’s health
Genetics
Other drugs used by the patient
Patient’s history of substance abuse.
Is Tramadol Good For Back Pain?
As you must have learned it by now, Tramadol is a drug that is mainly prescribed for the treatment of pain inside a human body. The pain that occurs is carried to the brain through the pain receptors present in the Central Nervous System (CNS). Patients should not buy Tramadol online if they do not have a prescription for the drug.
The dosage of Tramadol is prescribed when other non-opioid pain medications are not active enough on a person’s health. The immediate-release form of Tramadol is given to a patient when the pain is severe and needs to be treated then and there. These forms of Tramadol are not for recreational purposes. Doctors mainly prescribe the immediate-release form of Tramadol for back pain, postoperative pain after spine surgery, and sciatica (pain running through the sciatic nerve). Thus, Tramadol is a suitable drug to treat back pain.
Is Tramadol An Anti-Inflammatory?
No, Tramadol is not categorized as a nonsteroidal anti-inflammatory drug (NSAID). Instead, Tramadol is more of a synthetic drug that is produced by man. It belongs to the class of opioid analgesics that help in the treatment of pain. People who buy Tramadol online without a prescription may not have information about this.
An anti-inflammatory drug like aspirin is also used as a pain reliever, but it does have some harmful side effects. The anti-inflammatory drugs have a high risk of causing stomach ulcers or extreme pain, bleeding internally, high blood pressure, kidney or liver problems, and so on. Therefore, people who are taking Tramadol need not worry about the harmful effects of anti-inflammatory drugs.
Is Tramadol Good For Joint Pain?
Though there have been several uses of Tramadol related to pain, a person must not buy Tramadol online without knowing the issues it can treat. Tramadol, when combined with hydrochloride, is a centrally acting analgesic for pain that will double the mechanism of pain medication treatment.
The FDA has approved this combination for the management of moderate to severe pain. Doctors also prescribe this medication for the treatment of arthritis or joint pain followed by physical therapy.
Where Can You Buy Tramadol?
There are many websites and online pharmacies that sell Tramadol at a reasonable price. One must keep in mind not to buy Tramadol online without a prescription. It is illegal to purchase Tramadol without its prescription from a drug store or even through an online medium. Along with this, you need to be sure about the platform from where you will be purchasing your drug is authorized by the FDA (Food and Drug Administration).
Before you buy Tramadol online, do compare the prices and look for an official website. Some sellers in the online market are dealing in drugs that are low quality and higher pricing. You need to be aware of such frauds going on in and around the online market.
Medical College of Georgia, in its report, stated some facts regarding How well women affected with cervical cancer respond to treatment and survive with the level of 10 proteins in their blood that are associated with a “zombie” cell state called senescence.
The medical college scientists looked at the pre-treatment level of these types of proteins in the blood. It was around 565 in the women who have cervical cancer at the second or third stage, going through internal radiation treatment known as brachytherapy. They observed that ladies with a low level of proteins secreted by the senescent cells had a reasonable survival rate than those with high levels of these senescence-associated secreted phenotypes.
In addition to that, they also found that brachytherapy implants, a source of radiation close to the cervix. It improved patients’ survival with high levels of these SASPs but had little impact on low levels.
They mentioned in the journal cancer that the result of the experiment demonstrates that cellular senescence is a significant factor in determining survival and therapeutic response in cervical cancer and suggests that senescence reduction therapy may be a productive strategy to improve the therapeutic outcome of cervical cancer.
Dr. Jin-Xiong, director of the MCG Center for Biotechnology and Genomic Medicine, Georgia Research Alliance Eminent Scholar in Genomic Medicine, and the study’s author, said they want to figure out how to treat cervical cancer better than we do in the present situation. Beyond the stage and treatment modality, what other factors play a significant role in determining which patients survive cancer and how they respond to radiation therapy.
She further added that the study’s most important conclusion is to manage senescence to improve cervical cancer therapy to treat cancer survivors.
Dr. Sharad Purohit, a biochemist in MCG Center for Biotechnology and Genomic Medicine and the study’s author, said that in the women with moderate to high blood levels of SASPs in their blood. A class of drugs called senolytics, which targets these cells for elimination and is understudy to benefit age-related problems and disease—as an adjunct therapy could help them.
Cervical cancer is a common type of gynecological cancer caused due to the human papillomavirus. At the same time, it is mostly preventable by regular Pap smears that can detect early, precancerous changes or vaccines against HPV, and the survival rates for those who get it have been sluggish for decades.
According to the American cancer society, cancer survival rates have improved since the mid-1970s, except for cervical and endometrial cancer.
Dr. Sharad Purohit said that they observed levels of a total of 19 proteins and found that the cell’s secret in a pathological site like a precancerous or cancerous cervix. However, why the proteins form is a question they can’t yet answer.
They found that levels of ten proteins impacted cervical cancer survival in the women who were an average of 49-years-old. They all are associated with cellular senescence, either as the most destructive and inflammatory SASPs themselves or involved in regulating SASPs.
The scientist said that the cancer cells are associated with rapid reproduction that enables cancer’s growth; senescent cells cannot divide and reproduce. But they categorize these proteins as senescent cancer cells, which help create an inflammatory state in which cancer thrives and helps to lay down the groundwork for its spread. It also protects radiation therapy like chemotherapy and works in part by killing off typically rapidly dividing cancer cells. Senescent proteins change how cancer cells may respond to treatment.
Scientists also mentioned that they used machine learning for the experiment. Artificial intelligence enables the computers to figure out what the data means, link the high SASP level and low survival, and vice-versa.
